Treatment of Low Egg Reserve or Diminished Ovarian Reserve (DOR)
What is DOR? How is it related to infertility?
Diminished ovarian reserve (DOR) is the leading cause of infertility in women. It is characterized by a low number of eggs in a woman’s ovaries and/or poor quality of the remaining eggs, which boils down to impaired development of the existing eggs, even with assisted reproductive techniques. Limited knowledge about the reason behind low egg reserve.
Factors involved in DOR
DOR is a poor prognostic factor in ART, because of a decline in the quantity and quality of oocytes. Age is the major contributor to the low-risk factor. Diminished ovarian reserve is noted in women in their mid to late thirties, but it may affect younger women as well. It is believed that there is an accelerated decline in the follicular pool at the age of 37–38 when it reaches below a critical of 25,000.
Diagnosing Diminished Ovarian Reserve
Diminished ovarian reserve is diagnosed by evaluating specific hormone levels through ovarian reserve testing. Blood tests are used to measure levels of key hormones including AMH and FSH. AMH can be measured anytime in the menstrual cycle, while FSH needs to be measured early on in the cycle (typically cycle day 3). AMH and FSH are among the most important hormones for assessing female fertility in many situations: for young women considering fertility preservation, for women who have been trying to get pregnant, and for women who are poor responders to IVF.
Some fertility centers also use antral follicle count (AFC) to measure functional ovarian reserve. Follicles are tiny sacs in a woman’s ovaries that hold the developing oocytes. Antral follicle count is measured by looking at the number of antral follicles in the woman’s ovaries using transvaginal ultrasound. This test is performed during the first week of the menstrual cycle, typically between cycle day 2 and cycles day 5.
However, we find it most useful to focus on age-specific levels of AMH and FSH. Many centers neglect to consider age when they evaluate hormone levels, which can lead to misdiagnosis (or a missed diagnosis). Other hormones used in the infertility testing workup include estradiol, which is important because this hormone suppresses the FSH levels. Some fertility centers also test inhibin B.
Symptoms of DOR or Low Egg Reserve
Treatment of Diminished Ovarian Reserve (DOR) or Treatment of Low Egg Reserve
Treatment of Low Egg Reserve in women at Delhi IVF.
Most women who have been diagnosed with DOR (Diminished Ovarian Reserve) with high FSH levels or low AMH levels are advised by their reproductive endocrinologist that using donor eggs is probably an option left for pregnancy. However, that may not be always the case.
Diminished Ovarian Reserve can be treated in many cases. At Delhi IVF Research and Fertility Centre, we have ongoing studies on various applications of hormones/techniques to enhance the ovarian reserve or to use protocols that lead to successful treatment in women with DOR even without egg donation.
In many women, however, egg donation is the only resort to successful & healthy pregnancy. Delhi IVF has an excellent IVF egg donation program with consistently successful results over the last 30 years. We have one of the wide and excellent varieties of egg donors available for women, whose egg reserve is depleted, (all skin types/ Indian/ Caucasians/ different eye colors/ tall/ short / all religions), and those who are also extremely qualified.
We have successfully treated more than 5000 patients with Low Egg Reserve in the past 30 years and were able to successfully deliver a baby. Women with low egg reserve who cannot be treated also gained pregnancy through our Egg Donation Programme.
At Delhi IVF, we have developed age-specific hormone charts that enable us to be more accurate in defining the cause of infertility for women who are having problems getting pregnant naturally — as well as women who are poor responders to IVF. With a precise diagnosis, we can then provide highly personalized treatment.
Delhi IVF recommends testing for the FMR1 gene. This is typically associated with fragile X syndrome, and it has been known for a long time that some women with high CGG counts on this gene can develop premature ovarian failure. CGG counts on the FMR1 gene are predictors of future ovarian reserve.
Feeling very happy to have this type of experience. Just because of (IVF) we got twince babies in our life. Thanks you so much Dr. Anoop Gupta and his team. Thanks
First of all thanks to Delhi IVF centre & it’s all staff to bring happiest moment of our life. We feels proud every time we are here. One of the Best IVF centre I have visited ever. Staff is very co-operative. If someone will ask for IVF centre reference then definitely my answer will be Delhi IVF centre.
मेने डॉ. साहब का दिल से धन्यवाद करती हूँ क्यूंकि डॉ. साहब की कोशिश से हमारा सपना पूरा हुआ है | मुझे एक प्यारी सी बेटी की माँ बनने का सपना पूरा हुआ | मै बहुत खुश हूँ
We are so happy for the treatment of Dr. Gupta. We have so many problem in India before I tried many hospital for my wife and i found Delhi IVF. Thank you so much to the all team everyone was friendly with us. All the best for everyone.
I had the opportuned to see you early this year as regards my infertility problem and i am proud to inform you that i was delivered yesterday by C-section of a healthy 3.2 kg baby girl!!!! Many thanks to you, your lovely wife Dr. Alka and your dedicated management team. May God continue to bless you and the works of your hand.
Dear Dr. Anoop Gupta, & Team Greetings !!! Thanks You Once Again for changing our lives with your professional team and today we are living a happy and contented life as we got a gift with your efforts and medicines and our little Baby Girl Aaira was born on 20th February 2017 and our Family in now complete. My another friend Mr. Amin has shown his interest to visit your clinic and he wants to meet you and he has a great desire to have his treatment in your clinic.
Dear Dr. Aastha, Dr. Gupta and Team Hi from italy… I am so happy today Really want to thanks you. You’re so wonderful I had laparoscopy fibroid surgery few months ago. I went to see my doctor here in my country today and all my fibroids are gone. You have a done my surgery so sincerely you’re such a good human being can’t thank you enough I am so happy i had 2 surgeries earlier here in my city and both times I didn’t get better and it was the same. Now I am so happy May God Bless you
After long time my wishes fulfill. Thanks to Delhi IVF & Dr. Anoop Gupta & his team for giving me & my husband such a beautiful gift. Thank you very much.
Feeling very happy to have this type of experience. Just because of (IVF) we got twince babies in our life. Thanks you so much Dr. Anoop Gupta and his team. Thanks
Thank you to Dr. Anoop and his incredible team at Delhi IVF for bringing this bundle of joy to our family after a very long time.