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Repeated implantation failure refers to the failure to achieve pregnancy in an IVF cycle after transfer of at least three to four good-quality embryos in a minimum of three fresh or frozen cycles in a woman under the age of 40 years.
Successful IVF, IVF-ICSI is good procedures, but still in some cases in spite of repeated attempts with good embryos the procedure is not successful.
Successful embryo implantation requires synchronous development and interaction between the embryo and the endometrium. Recurrent implantation failure causes a lot of mental and financial stress on the infertile couple. It is also very difficult for the treating doctor to explain the reasons for not being successful in spite of everything being right. RIF may be both of embryonic or uterine factors or both.
Maternal blood tests
Hysteroscopy or endometrial scratching results in decidualization. There is some evidence that these procedures if done in the cycle before ovarian stimulation and IVF/ET increase the pregnancy rate in RIF patients.
Endometrial Receptivity Array – For a short period of time during the menstrual cycle after the embryo reaches the uterus, the receptivity to welcome embryo is called endometrial receptivity. This lasts for a short period and is called window of implantation (WOI). ERA is a reliable test to determine the time of window of implantation for any female and helps in personalized embryo transfer for patients in RIF for increasing the success rate of implantation.
The aim of the treatment should be such as to increase the chances of implantation and pregnancy. Effort should be made to increase the receptivity of endometrium and improve the quality of embryos. People have used immunomodulators to increase the receptivity of endometrium, scratching of the endometrium, PRP instillation and autologous stem cells. Intravenous injection of IgG is used to suppress immune responses in order to improve live birth rates.
If nothing works, the couple should be advised to go for surrogacy.
Do you want to discuss all your infertility problem with us? Delhi-IVF has a forum where we can discuss all about assisted reproductive technology over a cup of coffee.
Feeling very happy to have this type of experience. Just because of (IVF) we got twince babies in our life. Thanks you so much Dr. Anoop Gupta and his team. Thanks
First of all thanks to Delhi IVF centre & it’s all staff to bring happiest moment of our life. We feels proud every time we are here. One of the Best IVF centre I have visited ever. Staff is very co-operative. If someone will ask for IVF centre reference then definitely my answer will be Delhi IVF centre.
मेने डॉ. साहब का दिल से धन्यवाद करती हूँ क्यूंकि डॉ. साहब की कोशिश से हमारा सपना पूरा हुआ है | मुझे एक प्यारी सी बेटी की माँ बनने का सपना पूरा हुआ | मै बहुत खुश हूँ
We are so happy for the treatment of Dr. Gupta. We have so many problem in India before I tried many hospital for my wife and i found Delhi IVF. Thank you so much to the all team everyone was friendly with us. All the best for everyone.
I had the opportuned to see you early this year as regards my infertility problem and i am proud to inform you that i was delivered yesterday by C-section of a healthy 3.2 kg baby girl!!!! Many thanks to you, your lovely wife Dr. Alka and your dedicated management team. May God continue to bless you and the works of your hand.
Dear Dr. Anoop Gupta, & Team Greetings !!! Thanks You Once Again for changing our lives with your professional team and today we are living a happy and contented life as we got a gift with your efforts and medicines and our little Baby Girl Aaira was born on 20th February 2017 and our Family in now complete. My another friend Mr. Amin has shown his interest to visit your clinic and he wants to meet you and he has a great desire to have his treatment in your clinic.
Dear Dr. Aastha, Dr. Gupta and Team Hi from italy… I am so happy today Really want to thanks you. You’re so wonderful I had laparoscopy fibroid surgery few months ago. I went to see my doctor here in my country today and all my fibroids are gone. You have a done my surgery so sincerely you’re such a good human being can’t thank you enough I am so happy i had 2 surgeries earlier here in my city and both times I didn’t get better and it was the same. Now I am so happy May God Bless you
After long time my wishes fulfill. Thanks to Delhi IVF & Dr. Anoop Gupta & his team for giving me & my husband such a beautiful gift. Thank you very much.
Thank you to Dr. Anoop and his incredible team at Delhi IVF for bringing this bundle of joy to our family after a very long time.