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    Physiological Intracytoplasmic Sperm Injection

    It is Physiological Intracytoplasmic Sperm Injection (PICSI). It is a procedure of selecting the best possible sperm for based on physiological characteristic along with good motility and morphology, before injecting it into the egg as in normal intracytoplasmmic injection during an IVF protocol. This procedure helps us in picking a single mature sperm for injecting into the egg. Since it is known only a mature sperm can bind to the oocyte complex (Hyaluronan) to fertilize the egg, It helps to increase the chances of fertilization, implantation.


    Such mature sperms have fewer chromosomal abnormalities than the immature sperms. This procedure helps us in having the additional benefit over ICSI. This technique is possible, if the sperm count and motility is good in the ejaculate.

    PICSI Fertility Treatment in Delhi

    This technique is superior to ICSI as it gives consistently better results than ICSI. This technique also separates DNA fragmented sperms from normal sperms.

    The Principle:-

    • Expression of protein HspA2 indicating sperm maturation.
    • Remodeling of cytoplasmic membrane, resulting in formation of binding site on the sperm, for binding Zona pellucida of the oocyte.

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