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Polycystic
ovarian syndrome
(
PCOS),
also known as
PCOD
( polycystic ovarian disease) is
one of the commonest causes of
infertility.
The condition, polycystic
ovarian syndrome, known as PCOS,
is the commonest cause of
ovulation disorders in women of
reproductive age. Polycystic
ovarian syndrome (PCOS), is a
primary ovarian condition and is
characterized by the presence of
many minute cysts in the ovaries
and excess production of
androgens. Polycystic ovarian
syndrome can be found in
apparently normal women and the
full expression of the disease
so-called “Stein-leventhal
syndrome” is very uncommon.
Polycystic ovarian syndrome is
frequently associated with
weight gain, excessive hair
growth in the face and body,
irregular and infrequent periods
or absent periods, infrequent or
absent ovulation, miscarriage
and infertility. The cause of
PCOS is not fully understood.
However, PCOS is thiught to be a
genetic disorder (autosomal
dominant) meaning that each
child has a 50% chance of
inheriting the disorder from a
parent who carries the gene. The
gene can be inherited from
either mother or father. The
exact gene causing PCOS has not
yet been identified. There are
long-term risks of developing
type 2 diabetes, cardiovascular
disease and cancer of the womb.
Women diagnosed as having PCOS
before pregnancy have an
increased risk of developing
gestational diabetes.
Incidence of Polycystic
Ovarian Syndrome
Polycystic ovarian syndrome (PCOS)
accounts for 90% of women with
oligomenorrhoea (infrequent
periods) and 30% of women with
amenorrhoea (absent of periods)
and over 70% of women with an
ovulation.
Diagnosis of Polycystic Ovarian
Syndrome
Laparoscopy: Laparoscopy allows
direct inspection of the
ovaries; the ovaries are
enlarged and polycystic.
However, polycystic ovaries may
appear normal at laparoscopy.
Vaginal ultrasound scan
(better than abdominal):
The vaginal ultrasound may show
the typical PCOS appearance but
reliability varies with
expertise.
Blood hormone levels of LH, FSH,
androgens and SHBG
Ideally, these tests should be
performed during the first four
days of the cycle. If the women
has no period, then the test can
be performed anytime, and
repeated if the results do not
provide a clear picture. |